Article

A polymer that reinforces luminal barrier function and attenuates inflammation in murine colitis

2026-06-19

Abstract excerpt

<title>Abstract</title> <p>Wet epithelial surfaces are protected by mucus, a hydrated gel formed primarily by heavily glycosylated mucins that supports lubrication and limits microbial access to the epithelium. In the colon, barrier function depends on mucus properties that restrict bacterial penetration. Disruption of the mucus barrier integrity allows bacteria and bacterial toxins to contact the epithelium, pro...

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Identifiers and source

Literature Corpus work: 6df67b8f-3d97-52dd-9f97-ce0a2ecdbc74
DOI: 10.21203/rs.3.rs-8290892/v1

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