Article
The <i>PPE25 (Rv1787) - PE18 (Rv1788) - PPE26 (Rv1789)</i> gene cluster encodes an interacting protein pair and is involved in immune evasion by <i>Mycobacterium tuberculosis</i>
2023-04-07
Abstract excerpt
Mycobacterium tuberculosis (M. tb) the causative agent of human tuberculosis, encodes multiple virulence factors to subvert host immune responses. One such class of proteins is encoded by the multigenic PE_PPE family which accounts for 10% of its coding potential. A number of these genes occur in clusters, of which the PPE25(Rv1787)-PE18(Rv1788)-PPE26(Rv1789) locus alone, is organised in a PPE-PE-PPE arrangemen...
Topics
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- Antibiotic Resistance in Bacteria
- Diagnosis and treatment of tuberculosis
- Immunodeficiency and Autoimmune Disorders
- Infectious Diseases and Tuberculosis
- Mycobacterium research and diagnosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Tuberculosis Research and Epidemiology
Identifiers and source
- Literature Corpus work
- c5f0fd55-8979-58fb-aab5-d4a50628d02e
- DOI
- 10.1101/2023.04.07.535983
