Article
Immunoregulatory functions and expression patterns of PE/PPE family members: Roles in pathogenicity and impact on anti‐tuberculosis vaccine and drug design
1 Jun 2015
Abstract excerpt
The Mycobacterium tuberculosis genome was sequenced more than 15 years ago. It revealed a lot of interesting information, one of which was that 10% of the total coding capacity of the M. tuberculosis genome is dedicated to the PE/PPE family. There is a gradual expansion of these proteins from nonpathogenic to pathogenic mycobacteria, and there is increasing evidence that PE/PPE proteins play important roles in...
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