Article

The Matricellular Protein CCN5 (WISP2) inhibits Cellular Senescence in Cardiac Myocytes and Fibroblasts

2025-10-07

Abstract excerpt

<title>Abstract</title> <p> Cardiovascular diseases remain the leading cause of global mortality. Cellular senescence has recently been implicated in the pathogenesis of various cardiovascular diseases. Our group has previously shown that the matricellular protein CCN5 is a potent anti-fibrotic molecule capable of inhibiting and reversing cardiac fibrosis. In this study, we investigated whether CCN5 can modulate...

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Literature Corpus work: c5d47003-783d-5483-874f-a10a9515c351
DOI: 10.21203/rs.3.rs-7635827/v1

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