Article

Modified mRNA Mediated CCN5 Gene Transfer Ameliorates Cardiac Dysfunction and Fibrosis without Adverse Structural Remodeling

2024-04-29

Abstract excerpt

Modified mRNAs (modRNAs) are an emerging delivery method for gene therapy. In particular, the modRNA-based COVID-19 vaccines have proven that modRNA is a safe and effective therapeutic tool. Moreover, modRNA has the potential to treat various human diseases including cardiac dysfunction. Acute myocardial infarction (MI) is a major cardiac disorder that currently lacks curative treatment options. MI is commonly acc...

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Literature Corpus work: b0bea823-d094-521f-8b8c-f3700556d32b
DOI: 10.20944/preprints202404.1934.v1

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