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Identification of Prominin‐2 as a new player of cardiomyocyte senescence in the aging heart

17 May 2024

Abstract excerpt

The aging heart is characterized by a number of structural changes leading to ventricular stiffness, impaired resistance to stress and increased risk of developing heart failure (HF). Genetic or pharmacological removal of senescent cells has recently demonstrated the possibility to relieve some cardiac aging features such as hypertrophy and fibrosis. However, the contribution of the different cell types in...

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PMID: 38757782
DOI: 10.1111/acel.14204

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