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Strategies for neoantigen screening and immunogenicity validation in cancer immunotherapy (Review)

7 May 2025

Abstract excerpt

Cancer immunotherapy stimulates and enhances antitumor immune responses to eliminate cancer cells. Neoantigens, which originate from specific mutations within tumor cells, are key targets in cancer immunotherapy. Neoantigens manifest as abnormal peptide fragments or protein segments that are uniquely expressed in tumor cells, making them highly immunogenic. As a result, they activate the immune system,...

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Identifiers

PMID: 40342048
DOI: 10.3892/ijo.2025.5749

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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