Article

Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning & reduces neurodegeneration

2020-03-15

Abstract excerpt

<h4>Summary</h4> mRNA transport in neurons is a ubiquitous process but has been often overlooked as a contributor to disease. Mutations of transport granule protein hnRNPA2 cause hereditary proteinopathy of neurons, myocytes, and bone. Here, we examine transport granule component specificity, assembly/disassembly, and the link to neurodegeneration. hnRNPA2 transport granule components hnRNPF and ch-TOG interact w...

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Literature Corpus work: c5ce3fdc-14ff-55c1-8c6e-dcd885627d2d
DOI: 10.1101/2020.03.15.992768

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