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Article

Fli1 deficiency suppresses RALDH1 activity of dermal dendritic cells and related induction of regulatory T cells: a possible role in scleroderma

2020-03-16

Abstract excerpt

<title>Abstract</title> <p>Background Aldehyde dehydrogenase 1 (RALDH1)-producing dermal dendritic cells (DCs), a conventional DC subset regulating skin fibrosis, are decreased in the involved skin of patients with systemic sclerosis (SSc). In this study, we investigated the contribution of Fli1 deficiency, a potential predisposing factor of SSc, to the phenotypical alteration of RALDH1-producing dermal DCs by us...

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Literature Corpus work
c586de8c-0a3b-56b9-b286-4950ef3a9ac4
DOI
10.21203/rs.3.rs-17386/v1
Open publication

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Fli1 deficiency suppresses RALDH1 activity of dermal dendritic cells and related induction of regulatory T cells: a possible role in sclerodermaDOI 10.21203/rs.3.rs-17386/v1
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