Article

Human Cytomegalovirus Induces Significant Structural and Functional Changes in Terminally Differentiated Human Cortical Neurons

2023-03-06

Abstract excerpt

<h4>ABSTRACT</h4> Human cytomegalovirus (HCMV) is a highly prevalent viral pathogen that typically presents asymptomatically in healthy individuals despite lifelong latency. However, in 10-15% of congenital cases, this beta-herpesvirus demonstrates direct effects on the central nervous system, including microcephaly, cognitive/learning delays, and hearing deficits. HCMV has been widely shown to infect neural prog...

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Literature Corpus work: c57ee52d-3e25-5f73-8adb-61a77b239d97
DOI: 10.1101/2023.03.03.531045

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