Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Induced Pluripotent Stem Cell-Derived Models to Investigate Human Cytomegalovirus Infection in Neural Cells

27 Nov 2012

Abstract excerpt

Human cytomegalovirus (HCMV) infection is one of the leading prenatal causes of congenital mental retardation and deformities world-wide. Access to cultured human neuronal lineages, necessary to understand the species specific pathogenic effects of HCMV, has been limited by difficulties in sustaining primary human neuronal cultures. Human induced pluripotent stem (iPS) cells now provide an opportunity for such...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anesthesia and Neurotoxicity Research
Share to Cytomegalovirus and herpesvirus research
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23209593
DOI: 10.1371/journal.pone.0049700

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Induced Pluripotent Stem Cell-Derived Models to Investigate Human Cytomegalovirus Infection in Neural CellsPMID 23209593Read ↗

Human Cytomegalovirus Induces Significant Structural and Functional Changes in Terminally Differentiated Human Cortical NeuronsSemantic proximity Read ↗

Human cytomegalovirus induces significant structural and functional changes in terminally differentiated human cortical neuronsSemantic proximity Read ↗

Downregulation of Neurodevelopmental Gene Expression in iPSC-Derived Cerebral Organoids Upon Infection by Human CytomegalovirusSemantic proximity Read ↗

Human Cytomegalovirus Infection of Human Embryonic Stem Cell-Derived Primitive Neural Stem Cells Is Restricted at Several Steps but Leads to the Persistence of Viral DNASemantic proximity Read ↗

Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain OrganoidsSemantic proximity Read ↗

Human Cytomegalovirus Compromises Development of Cerebral OrganoidsSemantic proximity Read ↗

Downregulation of neurodevelopmental gene expression in iPSC-derived cerebral organoids upon infection by human cytomegalovirusSemantic proximity Read ↗

Induced pluripotent stem (iPS) cells as in vitro models of human neurogenetic disordersSemantic proximity Read ↗

Human Cytomegalovirus Disruption of Calcium Signaling in Neural Progenitor Cells and OrganoidsSemantic proximity Read ↗

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs).Semantic proximity Read ↗

Poor sensitivity of iPSC-derived neural progenitors and glutamatergic neurons to SARS-CoV-2Semantic proximity Read ↗

Effects of cytomegalovirus infection on embryogenesis and brain developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.