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Demuxalot: scaled up genetic demultiplexing for single-cell sequencing

2021-05-23

Abstract excerpt

<h4>ABSTRACT</h4> Demultiplexing methods have facilitated the widespread use of single-cell RNA sequencing (scRNAseq) experiments by lowering costs and reducing technical variations. Here, we present demuxalot : a method for probabilistic genotype inference from aligned reads, with no assumptions about allele ratios and efficient incorporation of prior genotype information from historical experiments in a multi-...

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Literature Corpus work
c547eb7f-75c0-5eef-a640-45ae55406f93
DOI
10.1101/2021.05.22.443646
Open publication

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Demuxalot: scaled up genetic demultiplexing for single-cell sequencingDOI 10.1101/2021.05.22.443646
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