Article

Individual-Based Modeling of Microbial Communities Integrating Genetic Mechanisms: A Case Study of LuxS-Mediated Quorum Sensing in Salmonella Typhimurium

2025-03-13

Abstract excerpt

We present a digital twin framework for simulating microbial communities at the single-cell level, integrating genetic mechanisms through individual-based modeling (IBM). This in silico approach enables the study of bacterial populations with bio-sensing capabilities and stochastic virulence expression, facilitating the design of biotechnological applications such as targeted drug delivery. By combining kinetic mo...

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Literature Corpus work: c5356348-6a42-56a7-9f6a-eb4ca77032af
DOI: 10.1101/2025.03.09.642204

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Individual-Based Modeling of Microbial Communities Integrating Genetic Mechanisms: A Case Study of LuxS-Mediated Quorum Sensing in Salmonella TyphimuriumDOI 10.1101/2025.03.09.642204Read

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