Article

Efficacy of cabazitaxel and androgen splicing variant-7 status in circulating tumor cells in Asian patients with metastatic castration-resistant prostate cancer.

2022-06-30

Abstract excerpt

BACKGROUND: Androgen receptor splice variant-7(AR-V7) expression in circulating tumor cells(CTCs) in metastatic castration-resistant prostate cancer (mCRPC) is associated with resistance to abiraterone and enzalutamide. We had objectives to determine whether cabazitaxel(CBZ) was equally effective in AR-V7 positive and negative CRPC, and if AR-V7 positive patients retained CBZ sensitivity. METHODS: This study was f...

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Literature Corpus work: c5044c7e-7b59-5020-93af-d6b869d6818d
DOI: 10.21203/rs.3.rs-1603022/v1

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