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Article

AR-V7 in Metastatic Prostate Cancer: A Strategy beyond Redemption.

International journal of molecular sciences - 24 May 2021

Sobhani Navid, Neeli Praveen Kumar, D'Angelo Alberto, Pittacolo Matteo, Sirico Marianna, Galli Ilaria Camilla, Roviello Giandomenico, Nesi Gabriella

Abstract excerpt

Metastatic prostate cancer is the most common cancer in males and the fifth cause of cancer mortality worldwide. Despite the major progress in this field, leading to the approval of novel anti-androgens, the prognosis is still poor. A significant number of patients acquire an androgen receptor splice variant 7 (AR-V7), which is constitutively activated and lacks the ligand-binding domain (LBD) while maintaining...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34073713
DOI: 10.3390/ijms22115515
PMCID: PMC8197232

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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