<scp>Androgen receptor</scp> splice variant 7 in castration‐resistant prostate cancer: Clinical considerations

Abstract excerpt

Constitutively-active ligand-independent splice variants of the androgen receptor are an adaptive response by prostate cancer cells to escape androgen deprivation therapy and novel androgen receptor-directed treatments. Androgen receptor splice variant 7 is the most common splice variant detected in clinical biospecimens, and emerging data now suggest that the presence of tumoral androgen receptor splice variant...

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