Article

Integrated analyses of the single-cell ATAC-seq and RNA-seq reveal the epigenetic landscape of human ovarian aging

2022-01-05

Abstract excerpt

<title>Abstract</title> <p>Studying the molecular mechanisms of ovarian aging is crucial for understanding the age-related fertility issues in females. Recently, a single-cell transcriptomic roadmap of ovarian aging based on non-human primates revealed the molecular signatures of the oocytes at different developmental stages. Herein, we present the first epigenetic landscape of human ovarian aging, through an int...

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Literature Corpus work: c5036b70-e22e-58be-a65f-9fe7c43fdd9d
DOI: 10.21203/rs.3.rs-1085959/v1

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