Article

Integrated analyses of the single-cell ATAC-seq and RNA-seq reveal the epigenetic landscape of human ovarian aging

2021-11-07

Abstract excerpt

Studying the molecular mechanisms of ovarian aging is crucial for understanding the age-related fertility issues in females. Recently, a single-cell transcriptomic roadmap of ovarian aging based on non-human primates revealed the molecular signatures of the oocytes at different developmental stages. Herein, we present the first epigenetic landscape of human ovarian aging, through an integrated analysis of the sing...

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Literature Corpus work: 5bbea40f-f9a4-5a34-9b85-3de9bdad265e
DOI: 10.1101/2021.11.07.467593

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