Article

The influence of CYP2D6 and CYP2C19 genetic variation on diabetes mellitus risk in people taking antidepressants and antipsychotics

2021-07-09

Abstract excerpt

<h4>Background</h4> CYP2D6 and CYP2C19 enzymes are essential in the metabolism of antidepressants and antipsychotics. Genetic variation in these genes may increase risk of adverse drug reactions. Antidepressants and antipsychotics have previously been associated with risk of diabetes. We examined whether individual genetic differences in CYP2D6 and CYP2C19 contribute to these effects. <h4>Methods</h4> We identifie...

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Literature Corpus work: c4f7c512-f371-54ef-9c85-230634bd3364
DOI: 10.1101/2021.07.07.21259926

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