Article
Generation of human iPSC-derived pancreatic organoids to study pancreas development and disease
2024-10-25
Abstract excerpt
The pancreas has vital endocrine and exocrine functions that can be affected by life-threatening diseases such as diabetes and pancreatic cancer. While animal models have been essential for understanding pancreatic development and disease, they are limited by their low-throughput and major species-specific molecular and physiological differences. Generating 3D in vitro models, such as organoids, that are physiolog...
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Identifiers and source
- Literature Corpus work
- c4f3fa63-332c-5a35-be90-5bdcb8f073c8
- DOI
- 10.1101/2024.10.24.620102