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Standardized GMP-compliant scalable production of human pancreas organoids

4 Mar 2020

Abstract excerpt

BACKGROUND: Organoids are three-dimensional in vitro-grown cell clusters that recapitulate key features of native organs. In regenerative medicine, organoid technology represents a promising approach for the replacement of severely damaged organs, such as the pancreas in patients with type 1 diabetes. Isolation human pancreas organoids (hPOs) in chemically defined serum-free culture media would be a major...

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PMID: 32127043
DOI: 10.1186/s13287-020-1585-2

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