Back to search

Article

Generation of human iPSC-derived pancreatic organoids to study pancreas development and disease

2025-06-10

Abstract excerpt

The pancreas has vital endocrine and exocrine functions that can be affected by life-threatening diseases such as diabetes and pancreatic cancer. Although animal models are essential for understanding pancreatic development and disease, they are limited by their low throughput and major species-specific molecular and physiological differences. Generating 3D in vitro models, such as organoids, that are physiologic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7f4e91d3-b8d5-5b99-8840-30142fdcf6c8
DOI
10.12688/f1000research.162496.1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Generation of human iPSC-derived pancreatic organoids to study pancreas development and diseaseDOI 10.12688/f1000research.162496.1
Generation of human iPSC-derived pancreatic organoids to study pancreas development and diseaseSemantic proximity
Pancreatic Progenitors and Organoids as a Prerequisite to Model Pancreatic Diseases and CancerSemantic proximity
Human pancreatic organoids derived from pluripotent stem cells recapitulate pancreatic organogenesisSemantic proximity
Pancreas organoid models of development and regenerationSemantic proximity
Islet organoid as a promising model for diabetesSemantic proximity
Exploring human pancreatic organoid modelling through single-cell RNA sequencing analysisSemantic proximity
The Potential of Pancreatic Organoids for Diabetes Research and TherapySemantic proximity
Standardized GMP-compliant scalable production of human pancreas organoidsSemantic proximity
The Science and Engineering of Stem Cell–Derived Organoids-Examples from Hepatic, Biliary, and Pancreatic TissuesSemantic proximity
Current Challenges Associated with the Use of Human Induced Pluripotent Stem Cell-Derived Organoids in Regenerative MedicineSemantic proximity
Modeling human liver organ development and diseases with pluripotent stem cell-derived organoidsSemantic proximity
Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoidsSemantic proximity
Select a neighboring publication to make it the new centre.