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Pancreatic Progenitors and Organoids as a Prerequisite to Model Pancreatic Diseases and Cancer

25 Feb 2019

Abstract excerpt

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are characterized by their unique capacity to stepwise differentiate towards any particular cell type in an adult organism. Pluripotent stem cells provide a beneficial platform to model hereditary diseases and even cancer development. While the incidence of pancreatic diseases such as diabetes and pancreatitis is increasing, the understanding...

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PMID: 30930950
DOI: 10.1155/2019/9301382

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