Article

Integrin-αVβ3 is a fundamental factor in medulloblastoma tumorigenicity and radioresistance: A new game for an old player

2023-03-10

Abstract excerpt

<h4>ABSTRACT</h4> Medulloblastoma (MB) is the most frequent solid tumor in children, localized in the brain’s posterior fossa. Its standard of care comprises maximal resection surgery followed by craniospinal irradiation and chemotherapy. Despite a long-term survival rate of 70%, wide disparities among patients have been observed. Relevant targets for naive and recurrent MB are urgently needed. Primary and recurr...

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Literature Corpus work: c4eeb5a2-5fcc-5775-88c2-afef44336ee8
DOI: 10.1101/2023.03.08.531652

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