Article

Size-dependent invasion and therapeutic phenotype of 42MGBA glioblastoma spheroids

2025-07-14

Abstract excerpt

<h4>ABSTRACT</h4> Glioblastoma (GBM) is one of the most common malignant brain tumors, with patient mortality driven by invasion into the surround brain microenvironment and drug resistance. Multicellular spheroids are increasingly a common model to study GBM invasion and drug response in engineered biomaterials. However, a key design feature of tumor spheroid studies is the size of each spheroid (number of cells...

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Literature Corpus work: c44daf52-999f-5b67-b9cf-0d7baa964bb0
DOI: 10.1101/2025.07.09.663980

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