Article

PDLIM2 Repression: A Common Mechanism in Viral Lung Infection

2025-09-15

Abstract excerpt

<h4>Background</h4> PDLIM2, a PDZ-LIM domain-containing protein expressed highest in the lung and immune cells, serves as a unique tumor suppressor and immune modulator, mainly by turning off the activation of the master transcription factors NF-κB and STAT3. While its role in cancer is established, the involvement of PDLIM2 in viral infection remains unclear. <h4>Results</h4> Here, we analyzed public gene expre...

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Literature Corpus work: c43d0539-d6be-53be-a2af-ff4cbe971ef9
DOI: 10.1101/2025.09.12.675949

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