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Article

Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma.

Leukemia - 1 Mar 2017

Wurster K D, Hummel F, Richter J, Giefing M, Hartmann S, Hansmann M-L, Kreher S, Köchert K, Krappmann D, Klapper W, Hummel M, Wenzel S-S, Lenz G, Janz M, Dörken B, Siebert R, Mathas S

Abstract excerpt

Apart from its unique histopathological appearance with rare tumor cells embedded in an inflammatory background of bystander cells, classical Hodgkin lymphoma (cHL) is characterized by an unusual activation of a broad range of signaling pathways involved in cellular activation. This includes constitutive high-level activity of nuclear factor-κB (NF-κB), Janus kinase/signal transducer and activator of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27538486
DOI: 10.1038/leu.2016.238
PMCID: PMC5339435

Genes

PDLIM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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