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IL-6 Evades KSHV-Mediated Hyperadenylation repression via CRM1-Dependent Nuclear Export

2025-06-05

Abstract excerpt

<h4>ABSTRACT</h4> RNA turnover is critical for regulating cellular homeostasis, with nuclear export representing a key step in mRNA fate. During infection by Kaposi’s Sarcoma-associated Herpesvirus (KSHV), widespread mRNA decay is mediated by the viral endonuclease SOX, which depletes cytoplasmic transcripts and induces secondary nuclear RNA processing defects. One such defect includes transcript hyperadenylation...

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Identifiers and source

Literature Corpus work
c4296a1e-cb9e-59a9-8b8f-112458386a7a
DOI
10.1101/2025.06.05.657986
Open publication

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IL-6 Evades KSHV-Mediated Hyperadenylation repression via CRM1-Dependent Nuclear ExportDOI 10.1101/2025.06.05.657986
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