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Article

IL-1R8 : a novel checkpoint regulating anti-tumor and anti-viral activity of NK cells

2018-01-01

Abstract excerpt

IL-1R8 is an Interleukin-1 receptor family member that acts as a negative regulator of IL-1 family receptor and Toll-like receptor (TLR) signaling. Both murine and human NK cells express high levels of IL-1R8 but its functional role in this cell type has not been described so far. Natural Killer (NK) cells are innate lymphoid-derived cells and are able to recognize damaged, stressed, viral infected or tumor cells,...

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Literature Corpus work
c4094bf9-b4b5-5b01-9948-7cbf428a1788
DOI
10.21954/ou.ro.0000dbbd
Open publication

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