Article
NK1.1+ CD8+ T cells escape TGF-β control and contribute to early microbial pathogen response.
Nature communications - 6 Oct 2014
Ruiz Anne L, Soudja Saidi M'Homa, Deceneux Cyril, Lauvau Grégoire, Marie Julien C
Abstract excerpt
Following microbial pathogen invasion, one of the main challenges for the host is to rapidly control pathogen spreading to avoid vital tissue damage. Here we report that an effector CD8(+) T-cell population that expresses the marker NK1.1 undergoes delayed contraction and sustains early anti-microbial protection. NK1.1(+) CD8(+) T cells are derived from CD8(+) T cells during priming, and their differentiation is...
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