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IL-1R8: A molecular brake of anti-tumor and anti-viral activity of NK cells and ILC

5 Feb 2023

Abstract excerpt

Interleukin-1 receptor family members (ILRs) and Toll-Like Receptors (TLRs) play pivotal role in immunity and inflammation and are expressed by most cell types including cells of both the innate and adaptive immune system. In this context, IL-1 superfamily members are also important players in regulating function and differentiation of adaptive and innate lymphoid cells. This system is tightly regulated in order...

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PMID: 36753974
DOI: 10.1016/j.smim.2023.101712

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