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Spontaneous Mutants of <i>Streptococcus sanguinis</i> with Defects in the Glucose-PTS Show Enhanced Post-Exponential Phase Fitness

2021-07-16

Abstract excerpt

Genetic truncations in a gene encoding a putative glucose-PTS protein ( manL , EIIAB Man ) were identified in subpopulations of two separate laboratory stocks of Streptococcus sanguinis SK36; the mutants had reduced PTS activities on glucose and other monosaccharides. Using an engineered mutant of manL and its complemented derivative, we showed that the ManL-deficient strain had improved bacterial viability in...

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Literature Corpus work
ba662205-80b9-5b63-bec1-dfa503ec065f
DOI
10.1101/2021.07.15.452590
Open publication

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