Article

SR8278 inhibits cell proliferation independent of REV-ERB

2025-05-30

Abstract excerpt

<title>Abstract</title> <p>Background The small molecule SR8278 was initially identified as an antagonist of the REV-ERB (reverse c-ERBAa) nuclear receptor proteins, which play an important role in metabolism and circadian rhythms. Though SR8278 has been shown to have beneficial physiological effects in a variety of preclinical disease contexts, its impact on gene expression and cell proliferation in keratinocyt...

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Literature Corpus work: c3e1ddd6-50ac-5a19-a22d-4e6112f6a3c3
DOI: 10.21203/rs.3.rs-6727727/v1

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