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The dynamic interaction of systemic inflammation and the hypothalamic-pituitary-adrenal (HPA) axis during and after major surgery

2021-08-17

Abstract excerpt

Major surgery and critical illness produce a potentially life threatening systemic inflammatory response. The hypothalamic-pituitary-adrenal (HPA) axis is one of the key physiological systems that counterbalances this systemic inflammation through changes in adrenocorticotrophic hormone (ACTH) and cortisol. These hormones normally exhibit highly correlated ultradian pulsatility with an amplitude modulated by circa...

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Literature Corpus work
c3c5f74e-4271-51f1-98be-e4aa9b2fd3db
DOI
10.1101/2021.08.16.456512
Open publication

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The dynamic interaction of systemic inflammation and the hypothalamic-pituitary-adrenal (HPA) axis during and after major surgeryDOI 10.1101/2021.08.16.456512
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