Article
Low- versus high-baseline epinephrine output shapes opposite innate cytokine profiles: presence of Lewis- and Fischer-like neurohormonal immune phenotypes in humans?
Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2008
Elenkov Ilia J, Kvetnansky Richard, Hashiramoto Akira, Bakalov Vladimir K, Link Amrey A, Zachman Keith, Crane Marianna, Jezova Daniela, Rovensky Jozef, Dimitrov Mariana A, Gold Philip W, Bonini Sergio, Fleisher Thomas, Chrousos George P, Wilder Ronald L
Abstract excerpt
Immunogenetic mechanisms operating within the immune system are known to influence cytokine profiles and disease susceptibility. Yet the role of the individual's neurohormonal background in these processes remains undefined. Hormonal imbalances are documented in immune-related diseases, but it is unclear whether this represents a secondary phenomenon or a primary "defect" related to specific neurohormonal immune...
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