Article
Pulsatility of 24-hour concentrations of circulating interleukin-1-alpha in healthy women: analysis of integrated basal levels, discrete pulse properties, and correlation with simultaneous interleukin-2 concentrations.
Neuroimmunomodulation - 1 Jan 2000
Licinio J, Wong M L, Altemus M, Bongiorno P B, Bernat A, Brabant G, Tamarkin L, Gold P W
Abstract excerpt
Even though it is widely known that interleukin (IL)-1 alpha acts at the local level, it is still uncertain whether IL-1 alpha is secreted into the circulation and acts at distant sites. We have tried to elucidate this by measuring 24-hour levels of total IL-1 alpha in six healthy female voluntee...
Topics
- Adolescent
- Adult
- Circadian Rhythm
- Cluster Analysis
- Female
- Genetic Variation
- Humans
- Interleukin-1
- Interleukin-2
- Reference Values
- Secretory Rate