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Molecular Pathways Resultant in Fever due to Inhibitory Effects of Binding PGE2 to Glucocorticoid Receptors

2020-01-15

Abstract excerpt

Thermoregulation is crucial to homeostasis, but the mechanisms of its dysfunction are still largely mysterious, including fever, which is generally the most disconcerting sign of a serious infection or disease. Theories on body temperature dynamics that aim to explain a fever, such as changes in an internal setpoint, have been proposed, but none can identify the fundamental molecular pathways that produce a fever....

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Literature Corpus work
6dd9650c-a290-5d75-af58-a541a390689b
DOI
10.1101/2020.01.14.907105
Open publication

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Molecular Pathways Resultant in Fever due to Inhibitory Effects of Binding PGE2 to Glucocorticoid ReceptorsDOI 10.1101/2020.01.14.907105
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