Article

A Polymeric Diet Rich in Transforming Growth Factor Beta 2 Does Not Reduce Inflammation in Chronic 2,4,6-trinitrobenzene Sulfonic Acid Colitis in Pre-pubertal Rats

2020-10-16

Abstract excerpt

<title>Abstract</title> <bold>Background:</bold> Pediatric Crohn’s disease is characterized by a higher incidence of complicated phenotypes. Murine models help to better understand the dynamic process of intestinal fibrosis and test therapeutic interventions. Pre-pubertal models are lacking. We aimed to adapt a model of chronic colitis to pre-pubertal rats and test if a polymeric diet rich in TGF-β2 could redu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c3b7738e-3656-54d5-80cc-d5d4bab62f4d
DOI: 10.21203/rs.3.rs-80098/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Polymeric Diet Rich in Transforming Growth Factor Beta 2 Does Not Reduce Inflammation in Chronic 2,4,6-trinitrobenzene Sulfonic Acid Colitis in Pre-pubertal RatsDOI 10.21203/rs.3.rs-80098/v1Read

Prebiotic Enriched Exclusive Enteral Nutrition Suppresses Colitis via Gut Microbiome Modulation and Expansion of Anti-inflammatory T Cells in a Mouse Model of Colitis.Semantic proximity Read

Fecal microbiota transfer from celiac patients induces immune and histopathological changes mirroring celiac disease in a rat modelSemantic proximity Read

The TNF ΔARE mouse as a model of intestinal fibrosisSemantic proximity Read

Oral exposure to Perfluorooctanoic acid disrupts the microbiota-gut-liver axis and enhances the severity of chemically induced colitis in miceSemantic proximity Read

Anti-fibrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn's Disease.Semantic proximity Read

Tributyrin Protects the Colon from DSS-induced ColitisSemantic proximity Read

M2 Macrophages and Phenotypic Modulation of Intestinal Smooth Muscle Cells Characterize Inflammatory Stricture Formation in Rats.Semantic proximity Read

Advancements in Inflammation Parallels Myopenia in Winnie Mice Model of Spontaneous Chronic ColitisSemantic proximity Read

β-sitosterol β-D-glucoside (BSSG) triggers intestinal inflammation in zebrafish and mouse models prior to neurodegeneration onsetSemantic proximity Read

Two rat strains develop different clinical signs of experimental colitis: does inflammation make all the difference?Semantic proximity Read

Bioactive fish collagen peptides weaken intestinal inflammation by orienting colonic macrophages phenotype through mannose receptor activation.Semantic proximity Read

A polymer that reinforces luminal barrier function and attenuates inflammation in murine colitisSemantic proximity Read