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Article

Prebiotic Enriched Exclusive Enteral Nutrition Suppresses Colitis via Gut Microbiome Modulation and Expansion of Anti-inflammatory T Cells in a Mouse Model of Colitis.

Cellular and molecular gastroenterology and hepatology - 1 Jan 2021

Lunken Genelle R, Tsai Kevin, Schick Alana, Lisko Daniel J, Cook Laura, Vallance Bruce A, Jacobson Kevan

Abstract excerpt

BACKGROUND & AIMS: Exclusive enteral nutrition (EEN) is used to treat pediatric Crohn's disease (CD), but therapeutic benefits are variable, and EEN can lead to microbial dysbiosis. Because of reported lower efficacy EEN is not routinely used to treat pediatric ulcerative colitis (UC). Inulin-type fructans (IN) beneficially modulate the gut microbiome and promote expansion of anti-inflammatory immune cells. We...

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Identifiers

PMID: 34214707
DOI: 10.1016/j.jcmgh.2021.06.011
PMCID: PMC8453203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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