Article

Advancements in Inflammation Parallels Myopenia in <i>Winnie</i> Mice Model of Spontaneous Chronic Colitis

2024-11-21

Abstract excerpt

<h4>Background</h4> Inflammatory bowel disease (IBD) is characterized by gastrointestinal inflammation and systemic complications, including muscle wasting. Musculoskeletal conditions have remained an unappreciated aspect of IBD. This study aimed to describe the Winnie mouse model’s skeletal muscle phenotype and functional alterations. This model spontaneously develops chronic colitis that closely resembles human...

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Literature Corpus work: 77054dea-11c8-50d8-a3a1-9a83861d1b54
DOI: 10.1101/2024.11.20.624215

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