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Article

Genetic interactions between the hedgehog co-receptors Gas1 and Boc regulate cell proliferation during murine palatogenesis.

Oncotarget - 29 Nov 2016

Xavier Guilherme M, Seppala Maisa, Papageorgiou Spyridon N, Fan Chen-Ming, Cobourne Martyn T

Abstract excerpt

Abnormal regulation of Sonic hedgehog (Shh) signaling has been described in a variety of human cancers and developmental anomalies, which highlights the essential role of this signaling molecule in cell cycle regulation and embryonic development. Gas1 and Boc are membrane co-receptors for Shh, which demonstrate overlapping domains of expression in the early face. This study aims to investigate potential...

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Identifiers

PMID: 27811357
DOI: 10.18632/oncotarget.13011
PMCID: PMC5346710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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