Article

CRELD2 is a novel modulator of calcium mobilisation and calcineurin- NFAT signalling during osteoclast differentiation

2022-03-25

Abstract excerpt

Cysteine rich with epidermal growth factor (EGF)-like domains 2 (CRELD2) is an endoplasmic reticulum (ER) resident chaperone protein with calcium binding properties. CRELD2 is an ER-stress regulated gene that has been implicated in the pathogenesis of skeletal dysplasias and has been shown to play an important role in the differentiation of chondrocytes and osteoblasts. Despite CRELD2 having an established role in...

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Literature Corpus work: c39e672a-6730-5b91-a0fd-80f5595c7298
DOI: 10.21203/rs.3.rs-1435321/v1

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