Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An Emerging Role for Ca2+/Calcineurin/NFAT Signaling in Cancerogenesis

1 Jan 2007

Abstract excerpt

The NFAT proteins are a family of Ca2+/calcineurin-responsive transcription factors primarily recognized for their central roles in T lymphocyte activation. Recent studies, however, have demonstrated that the vital role of NFAT signaling is by no means restricted to the immune system. NFAT proteins are potent mediators of Ca2+ signals in many mammalian cells and tissues and control, among others, important steps...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calpain Protease Function and Regulation
Share to Cardiac Ischemia and Reperfusion
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17245111
DOI: 10.4161/cc.6.1.3650

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An Emerging Role for Ca2+/Calcineurin/NFAT Signaling in CancerogenesisPMID 17245111Read ↗

NFAT Gene Family in Inflammation and CancerSemantic proximity Read ↗

NfatSemantic proximity Read ↗

Nuclear factor of activated T-cells transcription factors in the vasculature: the good guys or the bad guys?Semantic proximity Read ↗

NFAT proteins: emerging roles in cancer progressionSemantic proximity Read ↗

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and FunctionSemantic proximity Read ↗

Nuclear factor of activated T cells in cancer development and treatmentSemantic proximity Read ↗

Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development.Semantic proximity Read ↗

Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling.Semantic proximity Read ↗

Role of NFAT in the Progression of Diabetic AtherosclerosisSemantic proximity Read ↗

NFAT signaling dysregulation in cancer: Emerging roles in cancer stem cellsSemantic proximity Read ↗

Calcineurin signaling and NFAT activation in cardiovascular and skeletal muscle developmentSemantic proximity Read ↗

The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.