Article

Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in PSC

2021-11-01

Abstract excerpt

<h4>Objective</h4> Conflicting microbiota data exist for primary sclerosing cholangitis (PSC) and experimental models. Goal: Define complex interactions between resident microbes and their association in PSC patients by studying antibiotic-treated specific pathogen-free (SPF) and germ-free (GF) multi-drug-resistant 2 deficient ( mdr2 -/- ) mice. <h4>Design</h4> We measured weights, liver enzymes, RNA expressi...

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Literature Corpus work: c376dc99-db09-54e0-a110-3014eefc3362
DOI: 10.1101/2021.10.31.466701

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