Article

Cultured Bacteria Isolated from Primary Sclerosing Cholangitis Patient Bile Induce Inflammation and Cell Death

2024-10-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Primary sclerosing cholangitis (PSC) is a chronic liver disease characterized by inflammation and progressive fibrosis of the biliary tree. The pathogenesis of PSC remains poorly understood, and there are no effective therapeutic options. Previous studies have observed associations between changes in the colonic and biliary microbiome and PSC. We aimed to determine whether b...

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Literature Corpus work: 35146d3c-aeaf-59ca-b1df-f045a04cf8ae
DOI: 10.1101/2024.10.08.617321

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