Article

Novel Evolution of the Mineralocorticoid Receptor in Humans compared to Chimpanzees, Gorillas and Orangutans

2024-03-06

Abstract excerpt

<title>Abstract</title> <p>Five distinct full-length mineralocorticoid receptor (MR) genes have been identified in humans. These human MRs can be distinguished by the presence or absence of an in-frame insertion of 12 base pairs coding for Lys, Cys, Ser, Trp (KCSW) in their DNA-binding domain (DBD) and the presence of two amino acid mutations in their amino terminal domain (NTD). Two human MRs with the KCSW inser...

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Literature Corpus work: c3760f2b-aff5-5ffd-9d10-c2bcf94cb53e
DOI: 10.21203/rs.3.rs-3727261/v2

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