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Mineralocorticoid Receptors: Evolutionary and Pathophysiological Considerations

22 Feb 2011

Abstract excerpt

Mineralocorticoid receptors (MR), glucocorticoid receptors (GR), progesterone receptors (PR), and androgen receptors (AR) comprise a closely related subfamily within the human 49-member nuclear receptor family. These receptors and their cognate ligands play major roles in homeostasis, reproduction, growth, and development, despite which their evolution and diversification remains incompletely understood. Several...

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PMID: 21343255
DOI: 10.1210/en.2010-1444

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