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Genetic insights into the age-specific biological mechanisms governing human ovarian ageing

2023-03-17

Abstract excerpt

There is currently little evidence that the genetic basis of human phenotype varies significantly across the lifespan. However, time-to-event phenotypes are understudied and can be thought of as reflecting an underlying hazard, which is unlikely to be constant through life when values take a broad range. Here, we find that 74% of 245 genome-wide significant genetic associations with age at natural menopause (ANM)...

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Identifiers and source

Literature Corpus work
c375597b-19da-5e76-84c4-cb8c531a70b1
DOI
10.1101/2023.03.13.23287201
Open publication

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Genetic insights into the age-specific biological mechanisms governing human ovarian ageingDOI 10.1101/2023.03.13.23287201
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