Article
Systemic low-dose anti-fibrotic treatment attenuates ovarian aging in the mouse
2024-06-25
Abstract excerpt
The female reproductive system is one of the first to age in humans, resulting in infertility and endocrine disruptions. The aging ovary assumes a fibro-inflammatory milieu which negatively impacts gamete quantity and quality as well as ovulation. Here we tested whether the systemic delivery of anti-inflammatory (Etanercept) or anti-fibrotic (Pirfenidone) drugs attenuates ovarian aging in mice. We first evaluated...
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Identifiers and source
- Literature Corpus work
- c363911d-e208-550e-a190-97339424a432
- DOI
- 10.1101/2024.06.21.600035