Article

In Vitro Fertilization Accelerates Female Reproductive Aging Through Early Ovarian Failure

2025-10-14

Abstract excerpt

Reproductive aging is characterized by the progressive decline of reproductive function, with broad implications for overall health and longevity. Environmental factors, including assisted reproductive technologies (ART), can accelerate reproductive aging by promoting premature ovarian failure in females. In vitro fertilization (IVF), though widely used and generally considered safe, is associated with lasting eff...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8fb2160a-515f-5b11-82f7-b4de3b6f389a
DOI: 10.1101/2025.10.13.682153

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

In Vitro Fertilization Accelerates Female Reproductive Aging Through Early Ovarian FailureDOI 10.1101/2025.10.13.682153Read

The effects of superovulation and reproductive aging on the epigenome of the oocyte and embryoSemantic proximity Read

Aging of Oocyte, Ovary, and Human ReproductionSemantic proximity Read

Ovarian aging: mechanisms and intervention strategiesSemantic proximity Read

Age-associated changes in cumulus cells and follicular fluid: the local oocyte microenvironment as a determinant of gamete qualitySemantic proximity Read

Maternal age and gonadotrophin elevation cooperatively decrease viable ovulated oocytes and increase ootoxicity, chromosome-, and spindle-misalignments: ‘2-Hit’ and ‘FSH-OoToxicity’ mechanisms as new reproductive aging hypothesesSemantic proximity Read

Searching for female reproductive aging and longevity biomarkersSemantic proximity Read

Current understanding of ovarian aging.Semantic proximity Read

Oocyte aging: cellular and molecular changes, developmental potential and reversal possibilitySemantic proximity Read

Female germline stem cells: recent advances, opportunities, and challenges to overcomeSemantic proximity Read

Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypesSemantic proximity Read

Systematic characterization of the ovarian landscape across mouse menopause modelsSemantic proximity Read

Making a good egg: human oocyte health, aging, and in vitro developmentSemantic proximity Read